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| Home | > | Our Research | > | Winning projects | > | Screening for Depression and Anxiety, exploring high risk sub-groups of cardiac patients, and revealing their relation to morbidity, rehabilitation status and quality of life 1-year following CABG surgery. |
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| Screening for Depression and Anxiety, exploring high risk sub-groups of cardiac patients, and revealing their relation to morbidity, rehabilitation status and quality of life 1-year following CABG surgery. | |
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Dr. Rachel Dankner – The Gertner institute, Sheba medical center, Tel-Hashomer
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Abstract |
Objectives |
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(1) Assess the pre and post surgical prevalence of depression and anxiety (D&A) in a representative sample of Coronary Artery Bypass Grafting (CABG) patients using a short screening tool (HADS) (2) Identify sub-groups at an increased risk for developing D&A amongst CABG patients (3) Study the relationship between level of D&A and recovery 1-year post surgery.
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Working hypothesis |
| (1) Proportion of D&A will vary so that a higher rate will be found within specific sub-groups: i.e. women, elderly, patients with co-morbid medical conditions (2) There will be an association between pre-surgical level of D&A and 1-year level of D&A, depending on whether or not individuals had participated in cardiac rehabilitation programs during the post operative year (3) There will be an association between pre & post surgical level of D&A and patients' health outcomes and quality of life at 1-year follow-up.
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Methodology |
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A prospective study including a representative sample of 1110 CABG patients recruited from 5 cardiothoracic units in Israel, 30% of whom are insured by Maccabi. Participants take part in two interviews: (1) Baseline - before surgery (2) Follow-up - 12 months thereafter. Data collected include: demographics, co-morbidity, biochemical markers, medication use, medical service utilization, anthropometric measures, lifestyle habits, employment status, functional capacity, depression & anxiety, and quality of life. Information regarding co-morbidities and biochemical markers is collected from medical charts and documents. During follow-up interview the same information is collected again referring to the year after surgery. Patients are also asked about cardiac rehabilitation participation.
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Significance |
| Depression and anxiety are strong predictors of negative outcomes in coronary heart disease (CAD). CABG may in it self trigger the development and exacerbation of D&A, which in turn may retard patients' recovery following surgery. Early detection and prompt treatment, by means of pharmacotherapy, psychotherapy or some combination of both, is expected to improve patients' recovery and swift return to pre-surgical level of activity. Integrating an easy to administer screening instrument to detect D&A is a first step towards effective management of D&A in CAD patients in Israel. |
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